Drug Disease Interactions Examples

Tryamine rich food cheese liver yeast product and MAO inhibitors Phenelzeline etc leads Fatal risk of hypertensive crisis enhanced metabolism. For example ginkgo biloba may increase the effect of anticoagulants. One example is the interaction between warfarin Coumadin an anticoagulant blood thinner and. Examples of pharmacodynamic interactions are simultaneous administration of a NSAID and phenprocoumon additive interaction or of aspirin and ibuprofen antagonistic interaction. Ergot alkaloids may cause vasospastic reactions other than coronary artery vasospasm such as peripheral vascular reactions and colonic ischemia causing muscle pains numbness coldness pallor and cyanosis of the digits. In patients with compromised circulation persistent vasospasm may result in gangrene or death. For example a nasal decongestant containing pseudoephedrine increases blood pressure and thus has to be avoided by people who are hypertensive have high blood pressure.

Drug interactions occur on pharmacodynamic and pharmacokinetic levels.

5Other NSAIDssuch as keto-profen piroxicam sulindac diclo-fenac and ketorolachave been shown to have similar interactions with warfarin. Tryamine rich food cheese liver yeast product and MAO inhibitors Phenelzeline etc leads Fatal risk of hypertensive crisis enhanced metabolism. This can alter the way one or both of the drugs act in the body or cause unexpected side effects. One example is the interaction between warfarin Coumadin an anticoagulant blood thinner and. A common example would be drug-induced renal or hepatic dysfunction that reduces the elimination of another drug. 5Other NSAIDssuch as keto-profen piroxicam sulindac diclo-fenac and ketorolachave been shown to have similar interactions with warfarin.

Examples Of Common Drug Disease Interactions In Elderly Patients Download Table

Drug disease interactions examples. Examples of diseases that can cause a drug-disease interaction are chronic kidney disease or CKD. Grapefruit juice and Terfenadine Grapefruit. Drug-condition interactions occur when a drug worsens or exacerbates an existing medical condition.

In patients with compromised circulation persistent vasospasm may result in gangrene or death. A common example would be drug-induced renal or hepatic dysfunction that reduces the elimination of another drug. For example ginkgo biloba may increase the effect of anticoagulants.

One example is the interaction between warfarin Coumadin an anticoagulant blood thinner and. Examples Drug-Drug interaction Drug-Food interaction Drug-Disease interaction 10. For example a nasal decongestant containing pseudoephedrine increases blood pressure and thus has to be avoided by people who are hypertensive have high blood pressure.

Some drugs taken to treat a cold may worsen glaucoma. Nonsteroidal anti-inflammatory drugs NSAIDs such as diflunisal have been shown to increase the risk for gastrointestinal GI bleeding and the anticoagulant response of war-farin. Calcium supplements may reduce the absorption of thyroid supplements11 This review will fo-cus on drug-drug interaction DDI mechanisms and will include examples of common drug interactions.

Tetracycline or fluoroquinolones like ciprofloxacin with antacid or food containing divalent ions lead to formation of poorly soluble chelates or complexes which can not be absorbed. The 2 most common drug-disease interactions were use of first-generation calcium channel blockers in patients with congestive heart failure and use of aspirin in patients with peptic ulcer disease both 37. For example some beta-blockers taken for heart disease or high blood pressure can worsen asthma and make it hard for people with diabetes to tell when their blood sugar is too low.

5Other NSAIDssuch as keto-profen piroxicam sulindac diclo-fenac and ketorolachave been shown to have similar interactions with warfarin. Ergot alkaloids may cause vasospastic reactions other than coronary artery vasospasm such as peripheral vascular reactions and colonic ischemia causing muscle pains numbness coldness pallor and cyanosis of the digits. Drug interactions occur on pharmacodynamic and pharmacokinetic levels.

Indeed the most successful examples of drug repurposing so far have not involved a systematic approach. This can alter the way one or both of the drugs act in the body or cause unexpected side effects.

Examples Of Common Drug Disease Interactions In Elderly Patients Download Table

Examples Of Common Drug Disease Interactions In Elderly Patients Download Table

Examples Of Common Drug Disease Interactions In Elderly Patients Download Table

Examples Of Common Drug Disease Interactions In Elderly Patients Download Table

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Examples of pharmacodynamic interactions are simultaneous administration of a NSAID and phenprocoumon additive interaction or of aspirin and ibuprofen antagonistic interaction.

Some drugs taken to treat a cold may worsen glaucoma. This can alter the way one or both of the drugs act in the body or cause unexpected side effects. A common example would be drug-induced renal or hepatic dysfunction that reduces the elimination of another drug. Ergot alkaloids may cause vasospastic reactions other than coronary artery vasospasm such as peripheral vascular reactions and colonic ischemia causing muscle pains numbness coldness pallor and cyanosis of the digits. Drug-Disease Interactions Sometimes drugs that are helpful in one disease are harmful in another disorder. Drug-condition interactions occur when a drug worsens or exacerbates an existing medical condition. One example is the interaction between warfarin Coumadin an anticoagulant blood thinner and. Repurposing of sildenafil citrate for erectile dysfunction relied on. Tetracycline or fluoroquinolones like ciprofloxacin with antacid or food containing divalent ions lead to formation of poorly soluble chelates or complexes which can not be absorbed.

FOOD- DRUG INTERACTIONS. Tryamine rich food cheese liver yeast product and MAO inhibitors Phenelzeline etc leads Fatal risk of hypertensive crisis enhanced metabolism. In patients with compromised circulation persistent vasospasm may result in gangrene or death. Examples of pharmacodynamic interactions are simultaneous administration of a NSAID and phenprocoumon additive interaction or of aspirin and ibuprofen antagonistic interaction. This column usually deals with interactions that occur when one drug directly affects the pharmacokinetics or pharmacodynamics of a second drug. Drug interactions occur on pharmacodynamic and pharmacokinetic levels. This can alter the way one or both of the drugs act in the body or cause unexpected side effects.